EDUCATION
2012/9—2017/7Ph.D.: Renmin University of China (with Prof. Zhiping Li)
2008/9—2012/7B. Sc.: Qingdao University of Science & Technology
EMPLOYMENT
2024/03—nowAssoc. Prof.: School of Chemistry and Life Resources, Renmin University of China
2020/11—2024/03Assoc. Prof.: Department of Chemistry, Renmin University of China
2017/9—2020/8Postdoc.: McGill University/Lanzhou University (with Prof. Chao-Jun Li)
HONORS
“Second Prize for Outstanding Scientific Research”of Renmin University of China (2023)
National Postdoctoral Program for Innovative Talents (2017)
National Scholarship for Doctoral Students (2014, 2015)
Guang Hua Scholarship (2016)
The 10th 'Academic Rising Star' Award of Renmin University of China (2016)
“First Class Scholarship for Doctoral Students” of Renmin University of China (2012-2016)
RESEARCH INTERESTS
Organic Synthesis and Catalysis
Fluorine Chemistry
Radical Chemistry
Transition-Metal/NHC Catalysis
Fine Chemical Synthesis
PUBULICATIONS
To date, more than 70 SCI papers, including J. Am. Chem. Soc. (1 article), Angew. Chem. Int. Ed. (9 articles), Nat. Commun. (2 articles), Chem. Sci. (5 articles), ACS Catal. (3 articles) and others.
ORCID：https://orcid.org/0000-0002-2850-8952
GoogleScholar：https://scholar.google.com/citations?user='zhU8ieIAAAAJ&hl=zh-CN
Publication Lists:
[1]Qian, H.; Cheng, Z. P.; Luo, Y.; Lv, L.*; Chen, S.*; Li, Z.* Pd/IPrBIDEA-Catalyzed Hydrodefluorination of gem-Difluorocyclopropanes: Regioselective Synthesis of Terminal Fluoroalkenes. J. Am. Chem. Soc. 2024, 146, 24-32.
[2]Feng, Y.; Chen, S.; Lv, L.*; Yaremenko, I. A.*; Terent'ev, A. O.*; Li, Z.* Photocatalytic Sulfonyl Peroxidation of Alkenes via Deamination of N‑Sulfonyl Ketimines. Org. Lett.2024, 26, 1920-1925.
[3]Yan, Y.; Lu, W.; Qian, H.; Lv, L.*; Li, Z.*Pd-Catalyzed Ring-Opening of gem-Difluorocyclopropanes for the Mono- and Bis-Fluoroallylation of 1,3-Dicarbonyls. Chin.J. Org. Chem. 2024, 44, doi: 10.6023/cjoc202312003.
[4]Lv, L.*; Luo, Y.; Li, Z. Advances in the Synthesis of Organogermaniums Based on the Addition Reactions of Alkenes and Alkynes. Chin.J. Org. Chem. 2024, 44, doi: 10.6023/cjoc202401014.
[5]Lv, L.;Lu, G.; Luo, Y.; Gao, G.; Yan, X.; Xu, Z.; Yao, L.; Li, H.; Li, Z.* Reductive Amination Reaction — Preparation of m-Xylylenediamine from Isophthalaldehyde as an Example: Introduce a Comprehensive Experiment of Organic Chemistry. Univ. Chem.2024, ASAP.
[6]Qian, H.; Nguyen, H. D.; Lv, L.*; Chen, S.*; Li, Z.* Chemo-, Stereo- and Regioselective Fluoroallylation/Annulation of Hydrazones with gem-Difluorocyclopropanes via Tunable Palladium/NHC Catalysis. Angew. Chem. Int. Ed. 2023, 62, e202303271.
[7]Lou, C.; Feng, Y.; Huang, Q.; Lv, L.*; Li, Z.* Visible Light-Induced Decarboxylative Peroxidation of Carboxylic Acids: Metal-Free Synthesis of Benzyl Peroxides. Asian J. Org. Chem.2023, 12, e202300408.
[8]Yan, Y.; Qian, H.; Lv, L.*; Li, Z.*. Pd/NHC-Catalyzed Ring-Opening of gem-Difluorocyclopropanes with Malonates Via Selective C-C Bond Cleavage: Synthesis of Monofluoroalkenes. J. Org. Chem.2024, DOI: 10.1021/acs.joc.3c00744.
[9]Mao, K.; Lv, L.*; Li, Z.* Amine-Induced Selective C–C Bond Cleavage of 2,2,2-Trifluoroethyl Carbonyls for the Synthesis of Ureas and Amides. J. Org. Chem.2023, 88, 10137–10146.
[10]Lv, L.*; Qian, H. Developments and Applications of Allyl-(aza)allyl Coupling Reactions. Green Synth. Catal. 2023, 4, 190-205.
[11]Luo, Y.; Lv, L.*; Li, Z.* Light-promoted Germylation of Aryl Propiolamides/Alkynoates: Synthesis of Ge-Containing Spiro[4.5]trienones and Vinylgermanes. ChemCatChem 2023, 15, e202300467.
[12]Shu, S.; Wang, L.; Lv, L.*; Li, Z.*Copper-Catalyzed [3+2] Annulation of Pyridinium Ylides with α-CF3 Ketones: Synthesis of Functionalized 2-Fluoroindolizines. Asian J. Org. Chem.2023, 12, e202300075.
[13]Gao, G.; Lv, L.*; Li, Z.* Three-Component Reactions of 2,2,2-Trifluoroethyl Ketones, Aryl Azides and Aqueous Ammonia for the Synthesis of 4-Cyano-1,2,3-triazoles. Eur. J. Org. Chem.2023, e202301135.
[14]Lv, L.*; Qian, H.; Crowell, A. B.; Chen, S.*; Li, Z.* Pd/NHC-Controlled Regiodivergent Defluorinative Allylation of gem-Difluorocyclopropanes with Allylboronates. ACS Catal. 2022, 12, 6495-6505.
[15]Lv, L.*; Qian, H.; Li, Z.* Catalytic Diversification of gem-Difluorocyclopropanes: Recent Advances and Challenges. ChemCatChem2022, 14, e202200890.
[16]Liu, F.; Lv, L.*; Ma, Y.*; Li, Z.* Copper-Catalyzed Radical Difluoromethylation-Peroxidation of Alkenes: Synthesis of β-Difluoromethyl. Peroxides. Asian J. Org. Chem.2022, 11, e202200393.
[17]Wang, L.; Shu, S.; Lv, L.*; Li, Z.* Copper-Catalyzed Remote Trifluoromethylthiolation-Peroxidation of Unactivated Alkenes via 1,5-Hydrogen Atom Transfer. Tetrahedron Lett.2022, 104, 154029.
[18]Gao, G.; Mao, K.; Lv, L.*; Li, Z.* Three-Component Coupling of α-Trifluoromethyl Carbonyls, Azides and Amines for the Regioselective Synthesis of 1,4,5-Trisubstituted 1,2,3-Triazoles. Adv. Synth. Catal.2022, 364, 1402-1408.
[19]Luo, Y.; Xu, B.; Lv, L.*; Li, Z.* Copper-Catalyzed Three-Component Germyl Peroxidation of Alkenes. Org. Lett.2022, 24, 2425-2430.
[20]Luo, Y.; Lv, L.*; Li, Z.* Copper-Catalyzed Germyl-Azidation of Alkenes with Germanium Hydrides and Trimethylsilyl Azide. Org. Lett.2022, 24, 8052-8056.
[21]Ma, Y.; Lv, L.*; Li, Z.* β-Perfluoroalkyl Peroxides as Fluorinated C3-Building Blocks for the Construction of Benzo[4,5]imidazo[1,2-a]pyridines. J. Org. Chem.2022, 87, 1564-1573.
[22]Wang, L.; Lv, L.*; Li, Z.* Concomitant Functionalization of Two Different Ketones by Merging Brønsted Acid Catalysis and Radical Relay Coupling. Org. Chem. Front.2022, 9, 1561-1566.
[23]Lv, L.*; Qian, H.; Ma, Y.; Huang, S.; Yan, X.; Li, Z.* Ligand-Controlled Regioselective and Chemodivergent Defluorinative Functionalization of gem-Difluorocyclopropanes with Simple Ketones. Chem. Sci.2021,12, 15511-15518. (Hot paper)
[24]Lv,L.; Gao, G.; Luo, Y.; Mao, K.; Li, Z.* Three-Component Reactions of Alpha-CF3 Carbonyls, NaN3, and Amines for the Synthesis of NH-1,2,3-Triazoles. J. Org. Chem.2021, 86, 17197-17212.
[25]Lou, C.; Wang, X.; Lv, L.*; Li, Z.* Iron-Catalyzed Ring-Opening Reactions of Cyclopropanols with Alkenes and TBHP: Synthesis of 5-Oxo Peroxides. Org. Lett.2021, 23, 7608-7612.
[26]Luo, Y.; Tian, T.; Nishihara, Y.; Lv, L.*; Li, Z.* Iron-Catalysed Radical Cyclization to Synthesize Germanium-Substituted Indolo[2,1-a]isoquinolin-6(5H)-ones and Indolin-2-ones. Chem. Commun.2021, 57, 9276-9279.
[27]Wang, X.; Lou, C.; Lv, L.*; Li, Z.* Annulative pi-Extension (APEX) of Indoles to Pyrido[1,2-a]indoles Using 4-Oxo Peroxides as C4 Units. Org. Lett.2021, 23, 5978-5982.
[28]Ma, Y.; Chen, Y.; Lv, L.*; Li, Z.* Regioselective Synthesis of Emission Color‐Tunable Pyrazolo[1,5‐a]pyrimidines with β,β‐Difluoro Peroxides as 1,3‐Bis‐Electrophiles. Adv. Synth. Catal.2021, 363, 3233-3239.
[29]Wang, L.; Ma, Y.; Jiang, Y.; Lv, L.*; Li, Z.* A Mn-Catalyzed Remote C(sp3)-H Bond Peroxidation Triggered by Radical Trifluoromethylation of Unactivated Alkenes. Chem. Commun.2021, 57, 7846-7849.
[30]Lv, L.*; Li, C.-J.* Pd-Catalyzed Defluorinative Alkylation of gem-Difluorocyclopropanes: Switching Regioselectivity via Simple Hydrazones. Angew. Chem. Int. Ed.2021, 60, 13098-13104.
[31]Li, L.; Huang, S.; Mao, K.; Lv, L.*; Li, Z.* Synthesis of Isoxazoles via Cyclization of β-Fluoro Enones with Sodium Azide. Tetrahedron Lett.2021, 71, 153052.
[32]Lv, L.*; Li, C.-J.* Ruthenium Catalyzed β-Selective Alkylation of Vinylpyridines with Aldehydes/Ketones via N2H4 Mediated Deoxygenative Couplings. Chem. Sci.2021, 12, 2870-2875.
[33]Tian, T.; Wang, X.; Lv, L.*; Li, Z.* Iron-Catalyzed Acylation-Functionalization of Unactivated Alkenes with Aldehydes. Chem. Commun.2020, 56, 14637-14640.
[34]Yu, L. ‡; Lv, L. ‡; Qiu, Z.; Chen, Z.; Tan, Z.; Liang, Y.-F.; Li, C.-J.* Pd-Catalyzed Formal Hydroalkylation of Aryl-Substituted Alkynes with Hydrazones. Angew. Chem. Int. Ed.2020, 59, 14009-14013. (contributed equally) (Hot paper)
[35]Lv, L. ‡; Yu, L. ‡; Qiu, Z.; Li, C.-J.* Switch in Selectivity for the Formal Hydroalkylation of 1,3-Dienes and Enynes with Simple Hydrazones. Angew. Chem. Int. Ed.2020, 59, 6466-6472. (VIP paper)
[36]Lv, L. ‡; Zhu, D. ‡; Li, C.-J.* Direct Dehydrogenative Alkyl Heck-Couplings of Vinylarenes with Umpolung Aldehydes Catalyzed by Nickel. Nat. Commun. 2019, 10, 715.
[37]Lv, L. ‡; Qiu, Z. ‡; Li, J.; Liu, M.; Li, C.-J.* N2H4 as Traceless Mediator for Homo- and Cross- Aryl Coupling. Nat. Commun. 2018, 9, 4739.
[38]Lv, L. ‡; Zhu, D. ‡; Tang, J.; Qiu, Z.; Li, C.-C.; Gao, J.; Li, C.-J.* Cross-Coupling of Phenol Derivatives with Umpolung Aldehydes Catalyzed by Nickel. ACS Catal. 2018, 8, 4622-4627.
[39]Lv, L.; Zhu, D.; Qiu, Z.; Li, J.; Li, C.-J.* Nickel-Catalyzed Regioselective Hydrobenzylation of 1,3-Dienes with Hydrazones. ACS Catal. 2019, 9, 9199-9205.
[40]Zhu, D.‡; Lv, L.‡; Li, C.-C.; Ung, S.; Gao, J.; Li, C.-J.* Umpolung of Carbonyls as Alkyl Organometallic Reagent Surrogates for Palladium Catalyzed Allylic Alkylation. Angew. Chem. Int. Ed. 2018,57, 16520-16524. (contributed equally)
[41]Zhou, Z.-Z.‡; Liu, M.‡; Lv, L.‡; Li, C.-J.* Silver (I)-Catalyzed Widely Applicable Aerobic 1,2-Diol Oxidative Cleavage. Angew. Chem. Int. Ed. 2018, 57, 2616-2620. (contributed equally)
[42]Lv, L.*;Li, Z.* FeCl3-Catalyzed Regio-Divergent Carbosulfenylation of Unactivated Alkenes: Construction of Medium-Sized Ring. J. Org. Chem. 2018, 83, 10985-10994.
[43]Lv, L.; Li, Z.*Iron-Catalyzed Oxidative Cyclization of 1,6-Enones with Aldehydes: Synthesis of Functionalized 3,4-Dihydro-2H-pyrans. Chin. J. Chem.2017, 35, 303-306.
[44]Lv, L.; Li, Z.* Cycloalkylation of C(sp3)-H Bond with Neighboring Carboxylic Acid as Traceless Activating Group. J. Org. Chem.2017, 82, 2689-2702.
[45]Lv, L.; Snider, B. B.; Li, Z.* Total Synthesis and Structure Revision of (±)-Clavilactone D Through Selective Cyclization of an α,β-Dicarbonyl Peroxide. J. Org. Chem.2017, 82, 5487-5491.
[46]Lv, L.; Lu, S.; Chen, Y.; Li, Z.* Diastereoselective Building up Polycyclic Tetrahydrofurans via Tandem Annulation of 1,n-Enynes with Aliphatic Acids. Org. Chem. Front. 2017, 4, 2147-2152.
[47]Lv, L.; Li, Z.*Iron-Catalyzed Radical [2+2+2] Annulation of Benzene-Linked 1,7-Enynes with Aldehydes: Fused Pyran Compounds.Org. Lett. 2016, 18, 2264-2267.
[48]Lv, L.; Bai, X.; Yan, X.; Li, Z.* Iron-Catalyzed Decarbonylation Initiated [2+2+m] Annulation of Benzene-Linked 1,n-Enynes with Aliphatic Aldehydes. Org. Chem. Front. 2016, 3, 1509-1513.
[49]Lv, L.; Li, Z.*Fe-Catalyzed Cross-Dehydrogenative Couplings.Top. Curr. Chem. (Z)2016, 374, 38. (Invited review)
[50]Lv, L.; Lu, S.; Guo, Q.; Shen, B.; Li, Z.*Iron-Catalyzed Acylation-Oxygenation of Terminal Alkenes for the Synthesis of Dihydrofurans Bearing a Quaternary Carbon.J. Org. Chem. 2015, 80, 698-704.
[51]Lv, L.; Xi, H.; Bai, X.; Li, Z.*Iron-Catalyzed Convergent Radical Cyclization of Aldehydes with Two Alkenes to 3,4-Dihydropyrans. Org. Lett. 2015, 17, 4324-4327.
[52]Lv, L.; Qi, L.; Guo, Q.; Shen, B.; Li, Z.* Iron-Catalyzed Divergent Tandem Radical Annulation of Aldehydes with Olefins toward Indolines and Dihydropyrans.J. Org. Chem.2015, 80, 12562-12571.
[53]Lv, L.; Shen, B.; Li, Z.* Total Synthesis of (+)-Clavilactones A, B, and Proposed D through Iron-Catalyzed Carbonylation–Peroxidation of Olefin. Angew. Chem. Int. Ed. 2014, 53, 4164-4167.
[54]Zhu, D. ‡ Lv, L. ‡; Qiu, Z.; Li, C.-J.* Nickel-Catalyzed Cross-Coupling of Umpolung Carbonyls and Alkyl Halides. J. Org. Chem.2019,84, 6312−6322. (contributed equally)
[55]Kan, J.; Chen, Z.; Qiu, Z.; Lv, L.; Li, C.; Li, C.-J.* Umpolung Carbonyls Enable Direct Allylation and Olefination of Carbohydrates. Sci. Adv. 2022, 8, eabm6840.
[56]Li, C.-C.; Kan, J.; Qiu, Z.; Li, J.; Lv, L.; Li, C.-J.* Synergistic Relay Reactions to Achieve Redox- Neutral a-Alkylation of Olefinic Alcohols with Ruthenium(II)-Catalysis. Angew. Chem. Int. Ed.2020, 59, 4544-4549.
[57]Yao, J.; Chen, Z.; Yu, L.; Lv, L.; Cao, D.; Li, C.-J.* Palladium-Catalyzed Hydroalkylation of Methylenecyclopropanes with Simple Hydrazones. Chem. Sci.2020, 11, 10759-10763.
[58]Cao, D.; Chen, Z.; Lv, L.; Zeng, H.; Peng, Y.; Li, C.-J.* Light-Driven Metal-Free Direct Deoxygenation of Alcohols under Mild Conditions. iScience, 2020, 23, 101419.
[59]Tian, T.; Wang, X.; Lv, L.; Li, Z.* Iron-Catalyzed [2+2+2]Annulation of Aliphatic Bridged 1,n-Enynes with Aldehydes for the Synthesis of Fused Pyrans. E. J. Org. Chem. 2020, 4425-4428.
[60]Qiu, Z.; Lv, L.; Li, J.; Li, C.-C.; Li, C.-J.* Direct Conversion of Phenols into Primary Anilines with Hydrazine Catalyzed by Palladium. Chem. Sci. 2019, 10, 4775-4781.
[61]Li, C.-J.*; Huang, J.; Dai, X.-J.; Wang, H.; Chen, N.; Wei, W.; Zeng, H.; Tang, J.; Li, C.; Zhu, D.; Lv, L. An Old Dog with New Tricks: Enjoin Wolff-Kishner Reduction for Alcohol Deoxygenation and C-C Bond Formations. Synlett. 2019, 30, 1508-1524.
[62]Tang, J.; Lv, L.; Dai, X.-J.; Li, C.-C.; Li, L.; Li, C.-J.* Nickel-Catalyzed Cross-Coupling of Aldehydes with Aryl Halides via Hydrazone Intermediates. Chem. Commun. 2018, 54, 1750-1753.
[63]Li, J. ‡; Zhu, D. ‡; Lv, L.; Li, C.-J.* Radical Difluoromethylthiolation of Aromatics Enabled by Visible Light. Chem. Sci.2018, 9, 5781-5786.
[64]Liu, W. ‡; Liu, P. ‡; Lv, L.; Li, C.-J.* Metal-Free and Redox-Neutral Conversion of Organotrifluoroborates into Radicals Enabled by Visible Light. Angew. Chem. Int. Ed.2018, 57, 13499-13503.
[65]Bai, X.; Lv, L.; Li, Z.* Copper-Catalyzed Tandem Trifluoromethylation-Cyclization of Olefinic Carbonyls: Synthesis of Trifluoromethylated 2,3-Dihydrofurans and 3,4-Dihydropyrans. Org. Chem. Front. 2016, 3, 804-808.
[66]Zheng, X.; Lv, L.; Lu, S.; Wang, W.; Li, Z.* Benzannulation of Indoles to Carbazoles and Its Applications for Synthesis of Carbazole Alkaloids. Org. Lett.2014, 16, 5156-5159.
[67]Lou, C.; Lv, L.*;Li, Z.*Fe-Catalyzed Ring-Opening Reactions of Siloxy Cyclopropanes with Alkenes and TBHP: Synthesis of 4-Ester Peroxides. J. Organomet. Chem. 2022, 977, 122467.
[68]Lou, C.; Lv, L.; Li, Z.* Mn-Catalyzed Ring-Opening Peroxidation of Cyclobutanols: A Method for the Synthesis of 4-Oxo Peroxides. Adv. Synth. Catal.2022, 364, 3743-3748.
[69]Mao, K.; Ma, Y.; Lv,L.;Li, Z.* [4+1] Cyclization of α-CF3 Carbonyls with Hydrazides: Synthesis of 1,3,4-Oxadiazoles under Ambient Conditions. Asian J. Org. Chem.2022, 11, e202200334.
[70]Ma, Y.; Mao, K.; Chen, Y.; Lv,L.; Li, Z.* Tandem Defluorination/Annulation of α-CF3 Carbonyls with Bis-Nucleophiles: Stereodivergent Synthesis of 2-Alkylidene-1,3-Heterocycles. Tetrahedron Lett.2022, 100, 153902.
